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Astellas Pharma has won a preliminary victory in the ongoing dispute against Zydus Lifesciences.
Myrbetriq is a prescription medication used to treat overactive bladder (OAB). (Photo Credit: X)
Indian pharmaceutical giant Zydus Lifesciences has a lost patent battle with Tokyo-based Astellas Pharma. The US District Court for Delaware upheld the validity of a patent concerning Myrbetriq, a prescription medicine used to treat overactive bladder, in favour of Astellas.
“The Court concludes the Generics Manufacturers (Zydus and Lupin) did not prove their asserted invalidity defences by clear and convincing evidence,” the Delaware District Court’s ruling said.
In a regulatory filing to the BSE and NSE dated April 17, 2025, Zydus said, “The Court passed an order in favour of the innovator on the validity of the ‘780 patent. Infringement of the ’780 patent, damages, and any additional invalidity theories will be litigated at a consolidated jury trial in 2026.”
Following the legal setback, Zydus Lifesciences shares plummeted nearly 8% on Wednesday.
What is Myrbetriq?
Myrbetriq is a prescription medication used to treat overactive bladder (OAB) in adults with symptoms like urinary frequency, incontinence, or urgency. It is sometimes prescribed alongside solifenacin (Vesicare), according to Healthline. Additionally, Myrbetriq is used to treat neurogenic detrusor overactivity (NDO) in certain children, a condition where nerve problems cause an overactive bladder.
Myrbetriq contains the active ingredient mirabegron, a beta-3 adrenergic agonist. It comes in two extended-release forms: tablets taken orally and granules mixed with water to form a liquid suspension. Currently, Myrbetriq isn’t available as a generic medication.
What are Myrbetriq’s side effects?
Myrbetriq can cause various side effects, ranging from mild to serious. Mild side effects include:
– Back pain
– Constipation
– Dizziness
– Dry mouth
– Fast heartbeat
– Headache
– Joint pain
– Nausea
– Nasal and throat swelling (common cold-like symptoms)
– Urinary tract infection (UTI)
– Diarrhea
Serious side effects
Myrbetriq can cause serious side effects, although they are uncommon. If you experience any serious side effects, contact your doctor immediately or call emergency services if it’s a medical emergency. These include:
– high blood pressure
– urinary retention
– allergic reactions
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